I thought it was okay too - I'd rate it a little above mediocre at least. The live-action segments were kinda dull - thru every one of them, I just kept hoping they'd get back to the animated scenes as quickly as possible. I blame its failure not just on the Farrelly Bros, but on a weak script, really poor editing and a very unimpressive voice cast.
Whoever directed Shatner was an idiot to let him do his own thing. Shatner's comedy stuff is usually really funny, but Shatner tries to hard to act when he's using only his voice, and he overacts more than usual in OJ. I lost some of his dialog because of his particular style of the dramatic pause and his poor manner of phrasing.
I can't stand Chris Rock, and his performance in this movie made me like him even less. That flashback scene he narrates early in the movie has got to be one of the most boring narrations I've ever heard an actor give in a movie - I think I may have even dozed off during it. Chris Rock is NOT a voice actor. They should have tried to get Chris Tucker (Rush Hour, Money Talks) for the role - it might have improved the movie's performance at the B.O. somewhat.
David Hyde Pierce's performance is fair, but it's about what you'd expect from him if you've seen him on Frasier. (He was much funnier as the walking stick in "A Bug's Life".) And the Pierce/Rock duo is a horrible match up - their characters have no "chemistry". Even in the scenes where they're supposed to be "bonding" fall flat. They're just saying their lines to each other.
I think Laurence Fishbourne is a great actor and he has a cool voice, but the voice director was an idiot to make his character sound so stereotypical. Thrax looks cool, but the performance tries to be too hip (which is what other reviewers have said about the whole movie, and I agree). The only line I liked from him was when he sang, "Fiiiiiiii-yuh!"
Don't get me started on Brandy. She has a sexy quality to her voice, but she's not a voice actor. I thought she was wrong for the role as well. I'd much rather have heard someone like Jada Pinkett Smith or Halle Berry.
Oddly enough, my favorite voice performance in the entire movie is from Ron Howard, and he has dialog in only one scene in the whole movie, and it's not even really "on camera" because it was a political ad shown on TV.
But I really enjoyed the animation - I thought they did a fine job of meshing the 2D with the 3D animation. Drix's animation was reminiscent of the Iron Giant in a number of ways. And the backgrounds were very impressive.
It really is one of the worst voice casts for an animated film that I can remember. If it hadn't been for the animation, I wouldn't even rate it a 1 out of 10.
There are too many slow spots and not enough comedy - compounded with a weak script, poor editing, and an unimpressive voice cast - but overall I still thought it was fair. I liked it a lot more than "The Tigger Movie" anyway, and it's a heckuva lot better than watching any of the Pokemon movies.
I also thought it was a very creative concept that just wasn't developed thoroughly enough. It's been done before in such movies as "Innerspace" (and the movie it was spoofing --) and "Fantastic Voyage", but to have a whole active civilization inside the human body was a very clever concept, I thought. That's where most of the humor is too - I'm sure medical students and those in the profession will find it hilarious. And there are enough hidden gags in the movie to merit more than one viewing, but like Hatter, I recommend a DVD/video rental, or go watch it at the dollar theater. It's not worth $7, I'm sorry to say.
Hatter, did you catch the Clint Howard cameo, and the veiled Pokemon reference with a large bit of double-meaning? Those were my favorite "hidden" gags in the movie.