Why are Drawn Together and Iron Man: Armored Adventures on this list at all? Yeah, they had fans, but were either of these shows really that significant, enduring or groundbreaking? Other shows like Bob's Burgers and Gravity Falls are just too new, especially to be placed on the same list as iconic shows like The Flintstones, Rocky & Bullwinkle and Looney Tunes.
Ideally, TV Guide should place these shows on separate categories, like by era, rather than lumping them all together solely on the criteria of "this is popular", "this is hot right now" and "we, the editors, like this one".
It's like Homer Simpson said in "Bart VS Thanksgiving", "If you just put every flash-in-the pan cartoon in there, you turn the whole (thing) into a farce." Yeah, the list Darklordaviator linked to is better.