My pick would have to be for the despot - Dr. Doom. This guy can do it all - he's a technological genius that created his own country. While every other country fears and despises him his people love him and knows that he is only trying to protect them. Add to Doom's list that he's the second most powerful sorcerer on Earth (he even went to Hell and battled Mephisto to save his mothers soul) and you have a villain that can out fight you, out think you and out class you in any endeavor you pick. That is unless your name is Reed Richards.
"Never give in--never, never, never, never, in nothing great or small, large or petty, never give in except to convictions of honour and good sense. Never yield to force; never yield to the apparently overwhelming might of the enemy."
- Prime Minister Winston Churchill
"Si vis pacem, para bellum."