I'm reading the Ultimate Spiderman and X-Men comics and I like that they're reinventing everything. Starting from the beginning with a new spinn is perfect for me, because I don't know all about the history of everyone like the real fans.
As long as the writing is good and they keep everything interesting I won't mind if they do something I've seen before. If it gets tedious I'll just stop reading. But, I think it could last.