I will go first, of course!
Leap of Faith is a personal favorite of mine that I have seen several times on DVD that I am truly hoping will get put on DVD soon. The Steve Martin movie about an evangelist who gets to see more of God than he bargained for is based on real life evangelist Benny Hinn. And I think it makes a great movie. As for special features, commentary would be great with the actors and director, and I'd like to see any deleted footage there might be, TV spots with Steve Martin on talk shows talking about the movie, and perhaps a documentary about real life evangelists.
Accidental Tourist, with William Hurt and Geena Davis is another all time favorite of mine and is sorely missed on DVD. A true modern classic, this one needs to be seen again on DVD. Commentary, deleted scenes, and I'd also like to see something on the DVD about the book upon which the movie was based.
Lost Highway, Fire Walk with Me, Eraserhead, and any other David Lynch movie not yet currently on DVD in region one and in widescreen. And Blue Velvet and Straight Story need to be re-released with special editions. We need to have a version of Straight Story at least with the same bonus features as the Japanese edition.
I am sure I will think of more as the thread goes on, but those are the main ones I'd put down good money for.