Comic based movies with multiple villains, which ones could work?

[Antiyonder]

For the most part, having multiple supervillains in a film can make or break a film based off a comic book. I believe the big example of mistake was either Batman & Robin or Batman Forever. Films that didn't seem to do so bad with the multiple villains concept:

Batman (1960s Film)
X-Men (Given though since the X-Men are a group and mutants are trying to look out for each other)
Spider-Man 3 (It got more respect than the Batman film in the previous paragraph, even resulted in a Spider-Man Team Up live action style)

That said, in which way do you imagine multiple villains appearing without the story losing quality. So far I'd go with:

Spider-Man: The Chameleon and Kraven The Hunter (The stepbrother/business relationship. Could even add Electro to the dysfunctional family. I'm waiting for the Aniamted Series fans to flame me to orbit for this, ;) )

Fantastic Four: The Frightful Four (I'd say The Wizard, Trapster, Klaw and Thundra)

[launchpad25]

Don't forget Spidey, and The Sinister Six.

[Antiyonder]

Don't forget Spidey, and The Sinister Six.

Except at this point it would be a heck of a job assembling a roster as two of the well known ones wouldn't fit in the movieverse (Sandman and Doctor Octopus).

The reason why the Frightful Four works is due to the Fantastic Four being a superhero team. Cause solo those four villains wouldn't stand a chance. Kind off a twisted Fantastic Four. That and those particular villains wouldn't be able to hold the interest of non comic fans on their own.

[Cortez2301]

The Chris Nolan Batman movies seem to work as each villain is given his/her fair share of time in the story.There were 3 main villains in "Batman Begins" as well as quite a few minor ones.They all fitted in fine in the story.Spiderman 3 wasn't really crowded IMO.X3 was crowded but it was also part of the story.

[Silly McGooses]

Personally, I hated the way the "supervillains" were treated in BB. Neither had enough screentime and were dreadfully boring. I understand he wanted to make it realistic...but there was so much wasted potential. I really think too much was crammed in there.

You can't really go wrong with the one-villain-per film rule.

I think the villains worked really well in Batman Returns, but multiple villains were only okay because they robbed Batman of screentime.

[Anarky]

I don't believe we've seen the last of Prof. Crane. He's still on the loose. I believe Nolan will open the next feature w/ the hunt and capture of the Scarecrow before moving onto the likes of The Joker and the descension of Harvey Dent.

[Mynd Hed]

I thought Batman: Mask of the Phantasm worked well with both the titular character and the Joker.

[Lord Dalek]

Superman II (in both its incarnations) is the quintessential way of doing a multiple supervillain movie. Everybody was established in the last movie so no need for needless introductory exposition. Zod, Non, Ursa, and Lex have about as much screen time in both movies as necessary without getting tedious. And none of it distracts from Superman himself. Yay!