I don't know, Imaishi has his own studio now, Studio Trigger. I guess it's not unlikely that a collaboration could happen, though, it has for the Evangelion films.
Originally Posted by Gold Guy
Besides, I haven't seen Gurren Lagann yet, but from what I've heard, it seems to have ended in such a way that a sequel would require either mass retconning or a Rebuild-style reboot.
Originally Posted by Jacob T. Paschal