We know the Black and White games are going to be a little different from the previous generations, but I'm wondering how far the anime will deviate as well.
Using an original character as opposed to the female protagonist is one point, but the anime has never really followed the games. It would kind of be ironic for them to make only a few small changes as usual while GameFreak completely alters the formula for the video game.
Me personally, I just want something different out of Team Rocket. Make them stop following Ash and do their own thing instead, get rid of them completely, make them good guys, something, just stop beating them into the ground. It's both monotonous and cruel (even if they are fictional).
Also, should we be wary of an"Ash is going to catch Zoarark" movement, like what happened with Lucario, because I'd like to know now, so that I can avoid it.