Jojo's Bizarre Adventure
I've been reading this series for about a year now. And I've got to say, it's high on my list of favorite mangas.
That "WRYYYYYYY!" internet meme, and clips from the Playstation fighter got me interested, so I decided to check out Part I: Phantom Blood. The realistic art style and strange character designs were a bit of a turn off, but they grew on me as I read on.
I think Part IV is still my favorite. We got the most interesting Stands with unique powers, an easy-going Jojo, and Yoshikage Kira: one of the most messed up villains I've ever seen.
But still, even though I liked how Josuke was an easy-going nice guy, nothing can top Joseph Joestar and his mischevious punk antics. And he was even better as an old man in Part III.