That is a tough question. Anime has a definite following. Live action has a definite following. The two don't always cross over. Many people around my age (late 20's) don't know much about anime and dismiss it as merely a cartoon for kids. You look at films like Final Fantasy and Titan AE...many people didn't care to see them because they were a form of animation. I would certainly hope for it to happen. If anime became a mainstream cross-over medium, I'd be very happy. Mainly, IMO, it would have to be shown to be a viable and intelligent form of entertainment (not just a long commercial for a toy line) and not just something for kids to enjoy.